25º Congresso Brasileiro de Microbiologia

25º Congresso Brasileiro de Microbiologia

ResumoID:2573-2

Área: Microbiologia Clinica ( Divisão A )

DISTRIBUTION OF RIB GENE AMONG INVASIVE AND COLONIZING STREPTOCOCCUS AGALACTIAE (GBS)ISOLATES RECOVERED IN MISIONES, ARGENTINA

Lacszeski Margarita (UNaM); Keil Angela (UNaM); Oviedo Patricia (UNaM); Quiroga Marina (UNaM); Pegels Eduardo (UNaM); Vergara Marta (UNaM)

Resumo

GBS is an important cause of invasive infections in neonates. Several virulence factors have been identified and associated with the pathogenesis of GBS. Some serotypes, like III, V and Ia, are recognized as the major serotypes that cause invasive infections. It was reported that rib gene and Rib protein, encoded by rib gene, are present in the large majority of serotype III strains. Characterization of virulence-related genes of GBS isolates is considered as important since there is evidence that some proteins enconded by these genes may contribute to strain differences in virulence. Also, some of these proteins are immunogenic and they may play a future role in development of GBS vaccines.

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It was concluded that we needed more-extensive analysis of the virulence-related genes presents in our GBS isolates, including the relationship between rib gene and capsular serotype, to contribute with more useful epidemiological data.

Palavras-chave: rib gene, Streptococcus agalactiae, GBS

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