25º Congresso Brasileiro de Microbiologia

25º Congresso Brasileiro de Microbiologia

ResumoID:2013-2

Área: Microbiologia Clinica ( Divisão A )

PREVALENCE OF DIARRHEAGENIC ESCHERICHIA COLI IN CHILDREN FROM NORTHEASTERN BRAZIL

Ila Fernanda Nunes Lima (UFC); Josiane da Silva Quetz (UFC); Alexandre Havt (UFC); Lourrany Borges Costa (UFC); Jones Barbosa Lima Neto (UFC); Rosa Maria Salani Mota (UFC); James Nataro (UMMC); Aldo Ângelo Moreira Lima (UFC)

Resumo

INTRODUCTION: Among bacteria, diarrheagenic Escherichia coli (DEC) are some of the most frequently detected intestinal pathogens. We aimed to determine the prevalence of four DEC types in children with and without diarrhea in Fortaleza, Ceara, Brazil.

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RESULTS: At least one DEC was detected in 98.8% (82/83) stool samples of the diarrhea group and in 96.4% (160/166) in the control group. EPEC was the pathotype more frequent in the population under study (79.1%, 197/249), followed by STEC (77.5%, 193/249), EAEC (37.3%, 93/249), and EIEC (26,9%, 67/249). EPEC was found significantly more often in children with diarrhea (89.2%, 74/83) than in children without the disease (74.1%, 123/166) (p=0.008). EAEC and EIEC were detected with slightly higher frequencies in children with diarrhea, 41.0% (34/83) and 30.1% (25/83), respectively, when compared to children without diarrhea, 35.5% (59/166) and 25.3% (42/166), respectively, but with no significant difference. The prevalence of STEC was also similar among control children (78.3%, 130/166) and cases (75.9%, 63/83). None of the genes used for DEC diagnosis was exclusively found in children with diarrhea.

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FINANCIAL SUPPORT: FIC/NIH (USA) and CNPq (Brazil)

Palavras-chave: CHILDHOOD DIARRHEA, Escherichia coli, PCR DETECTION

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