<HTML><HEAD><TITLE>25º Congresso Brasileiro de Microbiologia </TITLE><link rel=STYLESHEET type=text/css href=css.css></HEAD><BODY aLink=#ff0000 bgColor=#FFFFFF leftMargin=0 link=#000000 text=#000000 topMargin=0 vLink=#000000 marginheight=0 marginwidth=0><table align=center width=700 cellpadding=0 cellspacing=0><tr><td align=left bgcolor=#cccccc valign=top width=550><font face=arial size=2><strong><font face=Verdana, Arial, Helvetica, sans-serif size=3><font size=1>25º Congresso Brasileiro de Microbiologia </font></font></strong><font face=Verdana size=1><b><br></b></font><font face=Verdana, Arial,Helvetica, sans-serif size=1><strong> </strong></font></font></td><td align=right bgcolor=#cccccc valign=top width=150><font face=arial size=2><strong><font face=Verdana, Arial, Helvetica, sans-serif size=1><font  size=1>ResumoID:977-1</font></em></font></strong></font></td></tr><tr><td colspan=2><br><br><table align=center width=700><tr><td>Área: <b>Micologia Médica ( Divisão B )</b><p align=justify><strong><FONT SIZE="2"><B STYLE="FONT-FAMILY: ARIAL,HELVETICA,SANS-SERIF;"><SPAN STYLE="FONT-SIZE: 11PT;">COMPLEXOS METÁLICOS DA CURCUMINA: ATIVIDADE਀䄀一吀䤀䘀�一䜀䤀䌀䄀 䘀刀䔀一吀䔀 䄀 䘀唀一䜀伀匀 䐀䔀 䤀一吀䔀刀䔀匀匀䔀 䌀䰀촀一䤀䌀伀⸀㰀⼀匀倀䄀一㸀㰀⼀䈀㸀㰀⼀䘀伀一吀㸀 
਀㰀⼀猀琀爀漀渀最㸀㰀⼀瀀㸀㰀瀀 愀氀椀最渀㴀樀甀猀琀椀昀礀㸀㰀戀㸀㰀甀㸀䴀愀爀椀愀 䄀瀀愀爀攀挀椀搀愀 搀攀 刀攀猀攀渀搀攀 匀琀漀椀愀渀漀昀昀 㰀⼀甀㸀㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀䴀愀爀挀椀氀攀渀攀  䌀漀椀洀戀爀愀 搀攀 伀氀椀瘀攀椀爀愀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀䌀愀爀漀氀椀渀攀  䈀愀爀挀攀氀漀猀 䌀漀猀琀愀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀吀栀愀椀猀  䘀甀爀琀愀搀漀 䘀攀爀爀攀椀爀愀 䴀愀最愀氀栀攀猀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀䬀愀爀椀渀愀  匀椀氀瘀愀 䴀漀渀琀攀椀爀漀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀䘀氀瘀椀愀 䴀愀爀椀愀  刀攀稀攀渀搀攀 搀愀 䴀愀琀愀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀䄀氀椀挀攀  䄀氀洀攀椀搀愀 䜀漀渀琀椀樀漀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀䜀椀猀攀氀攀  䄀氀洀攀椀搀愀 圀愀琀愀渀愀戀攀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀숀渀最攀氀漀  搀攀 䘀琀椀洀愀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㬀 㰀戀㸀䌀氀攀椀搀攀 嘀椀瘀椀愀渀攀  䈀甀稀愀渀攀氀氀漀 䴀愀爀琀椀渀猀 㰀⼀戀㸀  ⠀㰀椀㸀唀䘀䴀䜀㰀⼀椀㸀⤀㰀戀爀㸀㰀戀爀㸀㰀⼀瀀㸀㰀戀㸀㰀昀漀渀琀 猀椀稀攀㴀㈀㸀刀攀猀甀洀漀㰀⼀昀漀渀琀㸀㰀⼀戀㸀㰀瀀 愀氀椀最渀㴀樀甀猀琀椀昀礀 挀氀愀猀猀㴀琀爀攀猀㸀㰀昀漀渀琀 猀椀稀攀㴀㈀㸀㰀洀攀琀愀 栀琀琀瀀ⴀ攀焀甀椀瘀㴀∀䌀漀渀琀攀渀琀ⴀ吀礀瀀攀∀ 挀漀渀琀攀渀琀㴀∀琀攀砀琀⼀栀琀洀氀㬀 挀栀愀爀猀攀琀㴀甀琀昀ⴀ㠀∀㸀㰀洀攀琀愀 渀愀洀攀㴀∀倀爀漀最䤀搀∀ 挀漀渀琀攀渀琀㴀∀圀漀爀搀⸀䐀漀挀甀洀攀渀琀∀㸀㰀洀攀琀愀 渀愀洀攀㴀∀䜀攀渀攀爀愀琀漀爀∀ 挀漀渀琀攀渀琀㴀∀䴀椀挀爀漀猀漀昀琀 圀漀爀搀 ㄀㄀∀㸀㰀洀攀琀愀 渀愀洀攀㴀∀伀爀椀最椀渀愀琀漀爀∀ 挀漀渀琀攀渀琀㴀∀䴀椀挀爀漀猀漀昀琀 圀漀爀搀 ㄀㄀∀㸀㰀氀椀渀欀 爀攀氀㴀∀䘀椀氀攀ⴀ䰀椀猀琀∀ 栀爀攀昀㴀∀昀椀氀攀㨀⼀⼀⼀䌀㨀─㔀䌀唀猀攀爀猀─㔀䌀䌀愀爀漀氀椀渀攀─㔀䌀䄀瀀瀀䐀愀琀愀─㔀䌀䰀漀挀愀氀─㔀䌀吀攀洀瀀─㔀䌀洀猀漀栀琀洀氀㄀─㔀䌀　㄀─㔀䌀挀氀椀瀀开昀椀氀攀氀椀猀琀⸀砀洀氀∀㸀㰀漀㨀猀洀愀爀琀琀愀最琀礀瀀攀 渀愀洀攀猀瀀愀挀攀甀爀椀㴀∀甀爀渀㨀猀挀栀攀洀愀猀ⴀ洀椀挀爀漀猀漀昀琀ⴀ挀漀洀㨀漀昀昀椀挀攀㨀猀洀愀爀琀琀愀最猀∀ 渀愀洀攀㴀∀洀攀琀爀椀挀挀漀渀瘀攀爀琀攀爀∀㸀㰀⼀漀㨀猀洀愀爀琀琀愀最琀礀瀀攀㸀㰀℀ⴀⴀ嬀椀昀 最琀攀 洀猀漀 㤀崀㸀㰀砀洀氀㸀 
 <w:WordDocument>਀  㰀眀㨀嘀椀攀眀㸀一漀爀洀愀氀㰀⼀眀㨀嘀椀攀眀㸀 
  <w:Zoom>0</w:Zoom>਀  㰀眀㨀䠀礀瀀栀攀渀愀琀椀漀渀娀漀渀攀㸀㈀㄀㰀⼀眀㨀䠀礀瀀栀攀渀愀琀椀漀渀娀漀渀攀㸀 
  <w:PunctuationKerning/>਀  㰀眀㨀嘀愀氀椀搀愀琀攀䄀最愀椀渀猀琀匀挀栀攀洀愀猀⼀㸀 
  <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid>਀  㰀眀㨀䤀最渀漀爀攀䴀椀砀攀搀䌀漀渀琀攀渀琀㸀昀愀氀猀攀㰀⼀眀㨀䤀最渀漀爀攀䴀椀砀攀搀䌀漀渀琀攀渀琀㸀 
  <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText>਀  㰀眀㨀䌀漀洀瀀愀琀椀戀椀氀椀琀礀㸀 
   <w:BreakWrappedTables/>਀   㰀眀㨀匀渀愀瀀吀漀䜀爀椀搀䤀渀䌀攀氀氀⼀㸀 
   <w:WrapTextWithPunct/>਀   㰀眀㨀唀猀攀䄀猀椀愀渀䈀爀攀愀欀刀甀氀攀猀⼀㸀 
   <w:DontGrowAutofit/>਀  㰀⼀眀㨀䌀漀洀瀀愀琀椀戀椀氀椀琀礀㸀 
  <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel>਀ 㰀⼀眀㨀圀漀爀搀䐀漀挀甀洀攀渀琀㸀 
</xml><![endif]--><!--[if gte mso 9]><xml>਀ 㰀眀㨀䰀愀琀攀渀琀匀琀礀氀攀猀 䐀攀昀䰀漀挀欀攀搀匀琀愀琀攀㴀∀昀愀氀猀攀∀ 䰀愀琀攀渀琀匀琀礀氀攀䌀漀甀渀琀㴀∀㄀㔀㘀∀㸀 
 </w:LatentStyles>਀㰀⼀砀洀氀㸀㰀℀嬀攀渀搀椀昀崀ⴀⴀ㸀㰀℀ⴀⴀ嬀椀昀 ℀洀猀漀崀㸀㰀漀戀樀攀挀琀 
 classid="clsid:38481807-CA0E-42D2-BF39-B33AF135CC4D" id=ieooui></object>਀㰀猀琀礀氀攀㸀 
st1:*{behavior:url(#ieooui) }਀㰀⼀猀琀礀氀攀㸀 
<![endif]--><style>਀㰀℀ⴀⴀ 
 /* Style Definitions */਀ 瀀⸀䴀猀漀一漀爀洀愀氀Ⰰ 氀椀⸀䴀猀漀一漀爀洀愀氀Ⰰ 搀椀瘀⸀䴀猀漀一漀爀洀愀氀 
	{mso-style-parent:"";਀ऀ洀愀爀最椀渀㨀　挀洀㬀 
	margin-bottom:.0001pt;਀ऀ洀猀漀ⴀ瀀愀最椀渀愀琀椀漀渀㨀眀椀搀漀眀ⴀ漀爀瀀栀愀渀㬀 
	font-size:12.0pt;਀ऀ昀漀渀琀ⴀ昀愀洀椀氀礀㨀∀吀椀洀攀猀 一攀眀 刀漀洀愀渀∀㬀 
	mso-fareast-font-family:"Times New Roman";਀ऀ洀猀漀ⴀ昀愀爀攀愀猀琀ⴀ氀愀渀最甀愀最攀㨀䔀一ⴀ唀匀㬀紀 
@page Section1਀ऀ笀猀椀稀攀㨀㘀㄀㈀⸀　瀀琀 㜀㤀㈀⸀　瀀琀㬀 
	margin:70.85pt 3.0cm 70.85pt 3.0cm;਀ऀ洀猀漀ⴀ栀攀愀搀攀爀ⴀ洀愀爀最椀渀㨀㌀㘀⸀　瀀琀㬀 
	mso-footer-margin:36.0pt;਀ऀ洀猀漀ⴀ瀀愀瀀攀爀ⴀ猀漀甀爀挀攀㨀　㬀紀 
div.Section1਀ऀ笀瀀愀最攀㨀匀攀挀琀椀漀渀㄀㬀紀 
-->਀㰀⼀猀琀礀氀攀㸀㰀℀ⴀⴀ嬀椀昀 最琀攀 洀猀漀 ㄀　崀㸀 
<style>਀ ⼀⨀ 匀琀礀氀攀 䐀攀昀椀渀椀琀椀漀渀猀 ⨀⼀ 
 table.MsoNormalTable਀ऀ笀洀猀漀ⴀ猀琀礀氀攀ⴀ渀愀洀攀㨀∀吀愀戀攀氀愀 渀漀爀洀愀氀∀㬀 
	mso-tstyle-rowband-size:0;਀ऀ洀猀漀ⴀ琀猀琀礀氀攀ⴀ挀漀氀戀愀渀搀ⴀ猀椀稀攀㨀　㬀 
	mso-style-noshow:yes;਀ऀ洀猀漀ⴀ猀琀礀氀攀ⴀ瀀愀爀攀渀琀㨀∀∀㬀 
	mso-padding-alt:0cm 5.4pt 0cm 5.4pt;਀ऀ洀猀漀ⴀ瀀愀爀愀ⴀ洀愀爀最椀渀㨀　挀洀㬀 
	mso-para-margin-bottom:.0001pt;਀ऀ洀猀漀ⴀ瀀愀最椀渀愀琀椀漀渀㨀眀椀搀漀眀ⴀ漀爀瀀栀愀渀㬀 
	font-size:10.0pt;਀ऀ昀漀渀琀ⴀ昀愀洀椀氀礀㨀∀吀椀洀攀猀 一攀眀 刀漀洀愀渀∀㬀 
	mso-ansi-language:#0400;਀ऀ洀猀漀ⴀ昀愀爀攀愀猀琀ⴀ氀愀渀最甀愀最攀㨀⌀　㐀　　㬀 
	mso-bidi-language:#0400;}਀㰀⼀猀琀礀氀攀㸀 
<![endif]-->਀ 
<p class="MsoNormal" style="text-align: justify; font-family: Arial,Helvetica,sans-serif;"><font size="2"><span style="font-size: 11pt;">A freqüência਀搀攀 椀渀昀攀挀攀猀 昀切渀最椀挀愀猀 琀攀洀 愀甀洀攀渀琀愀搀漀 猀甀戀猀琀愀渀挀椀愀氀洀攀渀琀攀 渀愀猀 切氀琀椀洀愀猀 搀挀愀搀愀猀 搀攀瘀椀搀漀 
a fatores debilitantes do sistema imunológico como AIDS, transplantes, terapias਀愀渀琀椀挀愀渀挀攀爀最攀渀愀猀Ⰰ 甀猀漀 搀攀 最氀椀挀漀挀漀爀琀椀挀椀搀攀猀Ⰰ 搀攀渀琀爀攀 漀甀琀爀漀猀⸀ 伀 琀爀愀琀愀洀攀渀琀漀 
quimioterápico convencional encontra dificuldades com o pequeno número de਀搀爀漀最愀猀 愀渀琀椀昀切渀最椀挀愀猀 搀椀猀瀀漀渀瘀攀椀猀 攀 愀 漀挀漀爀爀渀挀椀愀 搀攀 攀昀攀椀琀漀猀 挀漀氀愀琀攀爀愀椀猀⸀ 䄀猀猀椀洀Ⰰ 漀 攀猀琀甀搀漀 
de novos medicamentos encontra relevância. A curcumina é um pó amarelo਀愀氀愀爀愀渀樀愀搀漀 攀渀挀漀渀琀爀愀搀漀 渀漀 爀椀稀漀洀愀 搀漀 愀愀昀爀漀 ⠀㰀椀 猀琀礀氀攀㴀∀∀㸀䌀甀爀挀甀洀愀 
longa</i>) e é imensamente utilizada como tempero, principalmente na culinária਀愀猀椀琀椀挀愀⸀ 䔀猀琀甀搀漀猀 搀愀 愀琀椀瘀椀搀愀搀攀 戀椀漀氀最椀挀愀 昀漀爀愀洀 爀攀愀氀椀稀愀搀漀猀 攀Ⰰ 搀攀渀琀爀攀 漀猀 攀昀攀椀琀漀猀 
benéficos, destacam-se o poder antiinflamatório, redução do colesterol, a਀愀琀椀瘀椀搀愀搀攀 愀渀琀椀挀渀挀攀爀Ⰰ 愀渀琀椀昀椀戀爀琀椀挀愀Ⰰ 愀渀琀椀瀀爀漀琀漀稀漀爀椀愀 攀 愀渀琀椀瘀椀爀愀氀⸀ 伀 漀戀樀攀琀椀瘀漀 搀漀 
presente trabalho é a avaliação da atividade antifúngica de complexos metálicos਀搀愀 挀甀爀挀甀洀椀渀愀 昀爀攀渀琀攀 愀 昀甀渀最漀猀 搀攀 椀渀琀攀爀攀猀猀攀 洀搀椀挀漀⸀ 一漀瘀攀 挀漀洀瀀氀攀砀漀猀 昀漀爀愀洀 琀攀猀琀愀搀漀猀Ⰰ 
entre eles, quatro complexos metálicos da curcumina, quatro sais metálicos਀搀攀猀猀攀猀 挀漀洀瀀氀攀砀漀猀 攀 愀 瀀爀瀀爀椀愀 挀甀爀挀甀洀椀渀愀⸀ 伀 琀攀猀琀攀 昀漀椀 爀攀愀氀椀稀愀搀漀 瀀攀氀漀 洀琀漀搀漀 搀愀 
concentração inibitória mínima. Foram feitas três diluições dos compostos: 250,਀㄀㈀㔀 攀 㘀㈀Ⰰ㔀 딀最⼀洀氀⸀ 䄀猀 攀猀瀀挀椀攀猀 搀攀 昀甀渀最漀猀 琀攀猀琀愀搀愀猀 昀漀爀愀洀㨀 㰀椀 猀琀礀氀攀㴀∀∀㸀䌀愀渀搀椀搀愀 愀氀戀椀挀愀渀猀㰀⼀椀㸀Ⰰ 㰀椀 猀琀礀氀攀㴀∀∀㸀䌀愀渀搀椀搀愀 欀爀甀猀攀椀㰀⼀椀㸀Ⰰ 
<i style="">Candida parapsilosis</i>, <i style="">Candida tropicalis</i>, <i style="">Candida glabrata</i>, <i style="">Candida dubliniensis</i>,਀㰀椀 猀琀礀氀攀㴀∀∀㸀䌀爀礀瀀琀漀挀漀挀挀甀猀 渀攀漀昀漀爀洀愀渀猀㰀⼀椀㸀Ⰰ 㰀椀 猀琀礀氀攀㴀∀∀㸀匀瀀漀爀漀琀栀爀椀砀 猀挀栀攀渀挀欀椀椀㰀⼀椀㸀Ⰰ 㰀椀 猀琀礀氀攀㴀∀∀㸀䄀猀瀀攀爀最椀氀氀甀猀 昀甀洀椀最愀琀甀猀㰀⼀椀㸀Ⰰ 㰀椀 猀琀礀氀攀㴀∀∀㸀䄀猀瀀攀爀最椀氀氀甀猀 渀漀洀椀甀猀㰀⼀椀㸀 攀 㰀椀 猀琀礀氀攀㴀∀∀㸀倀愀爀愀挀漀挀挀椀搀椀漀椀搀攀猀 戀爀愀猀椀氀椀攀渀猀椀猀㰀⼀椀㸀⸀ 吀漀搀漀猀 
compostos foram eficientes contra <i style="">Paracoccidioides਀戀爀愀猀椀氀椀攀渀猀椀猀㰀⼀椀㸀⸀ 伀猀 挀漀洀瀀漀猀琀漀猀 搀攀 㰀猀琀㄀㨀洀攀琀爀椀挀挀漀渀瘀攀爀琀攀爀 瀀爀漀搀甀挀琀椀搀㴀∀㜀 愀∀ 眀㨀猀琀㴀∀漀渀∀㸀㜀 
 a</st1:metricconverter> 9 inibiram crescimento de <i style="">Cryptococcus neoformans</i>. Os compostos 2, 4, 8 e 9 impediram਀挀爀攀猀挀椀洀攀渀琀漀 搀攀 㰀椀 猀琀礀氀攀㴀∀∀㸀匀瀀漀爀漀琀栀爀椀砀 猀挀栀攀渀挀欀椀椀㰀⼀椀㸀⸀ 
O composto 7 foi eficiente contra <i style="">C.਀最氀愀戀爀愀琀愀㰀⼀椀㸀Ⰰ 㰀椀 猀琀礀氀攀㴀∀∀㸀䌀⸀ 欀爀甀猀攀椀㰀⼀椀㸀 攀 㰀椀 猀琀礀氀攀㴀∀∀㸀䌀⸀ 瀀愀爀愀瀀猀椀氀漀猀椀猀㰀⼀椀㸀 攀 挀漀洀瀀漀猀琀漀 㠀 椀渀椀戀椀甀 
crescimento de <i style="">C. krusei</i>.<o:p></o:p></span></font></p>਀ 
<p class="MsoNormal" style="text-align: justify; font-family: Arial,Helvetica,sans-serif;"><font size="2"><span style="font-size: 11pt;"><o:p>&nbsp;</o:p></span></font></p>਀ 
<p class="MsoNormal" style="text-align: justify;"><span style="font-size: 11pt;"><font size="2"><span style="font-family: Arial,Helvetica,sans-serif;">Apoio:਀䌀䄀倀䔀匀Ⰰ 䘀䄀倀䔀䴀䤀䜀 攀 䌀一倀焀⸀㰀⼀猀瀀愀渀㸀㰀⼀昀漀渀琀㸀㰀漀㨀瀀㸀㰀⼀漀㨀瀀㸀㰀⼀猀瀀愀渀㸀㰀⼀瀀㸀 
਀ 
਀㰀⼀昀漀渀琀㸀㰀⼀瀀㸀㰀戀爀㸀㰀戀㸀倀愀氀愀瘀爀愀猀ⴀ挀栀愀瘀攀㨀 㰀⼀戀㸀☀渀戀猀瀀㬀䄀琀椀瘀椀搀愀搀攀 愀渀琀椀昀切渀最椀挀愀Ⰰ 䌀甀爀挀甀洀椀渀愀Ⰰ 䌀愀渀搀椀搀愀 猀瀀瀀㰀⼀琀搀㸀㰀⼀琀爀㸀㰀⼀琀愀戀氀攀㸀㰀⼀琀爀㸀㰀⼀琀搀㸀㰀⼀琀愀戀氀攀㸀㰀⼀戀漀搀礀㸀㰀⼀栀琀洀氀㸀 