| Congresso Brasileiro de Microbiologia 2023 | Resumo: 1298-2 | ||||
Resumo:Domestic animals have an important role as reservoirs of Enterobacteriaceae MDR and ESBL producers, representing a high risk because can infect other pets and their owners. Studies on bacteria isolated from urinary tract infections (UTIs) indicate a high prevalence of Enterobacteriaceae. However, few studies have delved into the detection of MDR Enterobacteriaceae isolated from skin infections, in which owners may have more contact. For this reason, this study aimed to determine the prevalence of MDR enterobacterales in dogs isolated from dermal infections versus to UTIs. We evaluated antibiograms results from dogs of different ages, breeds, and sexes treated at private veterinarians located in Lima and Callao from January to August 2021.
As a result, a total of 376 samples was analyzed, 60.6% were from UTIs and 30.9% from skin infections. However, no statistically significant association (p>0.05) with MDR was found. In our study, the group of enterobacterales that produce beta-lactamase enzymes was reduced, however among ESBL producers, 97.4% were MDR. Furthermore, it was shown that the prevalence of Klebsiella spp. MDR was 1,57 (IC95% 1,14 – 2,14; p<0.05) higher than the prevalence of E. coli MDR, adjusted for sex, age, race, location, and type of infection. Likewise, the prevalence of enterobacterales MDR in samples from East of Lima was 1,89 (IC 95% 1,36 – 2,62; p<0.001) times the prevalence of MDR bacteria in Central Lima, adjusted for sex, age, race, and type of infection. As a conclusion, no difference was found between the area of infection (dermal or urinary) and MDR. Likewise, a third of the dogs infection samples were ESBL producers and 97,4% MDR. It was observed an association between the presence of MDR with the location of residence and the bacterial genus. Palavras-chave: Enterobacteriaceae, Dog, Multidrug resistance, ESBL Agência de fomento:Fogarty International Center of the US National Institutes of Health | |||||