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Congresso Brasileiro de Microbiologia 2023
 		Resumo: 434-1

434-1

GLOBAL DISTRIBUTION OF ANTIMICROBIAL RESISTANCE IN PATHOGENIC Escherichia coli ISOLATED FROM CALVES: A SYSTEMATIC REVIEW

Autores:
Dircéia Aparecida Costa Custódio Costa (UFLA - Universidade Federal de Lavras) ; Amanda Carvalho Rosado Ferreira (UFLA - Universidade Federal de Lavras) ; Maysa Serpa Gonçalves (UFLA - Universidade Federal de Lavras) ; Anna Cecília Trolesi Reis Borges Costa (UFLA - Universidade Federal de Lavras) ; Carine Rodrigues Pereira (UFLA - Universidade Federal de Lavras, IFMG - CAMPUS BAMBUÍ - Instituto Federal de Minas Gerais - Campus Bambuí) ; Fernanda Morcatti Coura (IFMG - CAMPUS BAMBUÍ - Instituto Federal de Minas Gerais - Campus Bambuí) ; Andrey Pereira Lage Pereira Lage (UFMG - Universidade Federal de Minas Gerais) ; Geraldo Marcio da Costa (UFLA - Universidade Federal de Lavras) ; Elaine Maria Seles Dorneles Maria Seles Dorneles (UFLA - Universidade Federal de Lavras)

Resumo:
The present study aimed to perform a systematic review to determine the antimicrobial resistance profile of pathogenic Escherichia coli strains isolated from intestinal tract of calves worldwide. Six databases were systematically searched (CABI, Cochrane, Pubmed, Scielo, Scopus and Web of Science) with no restrictions regarding the year or place of the publications. A total of 932 studies were recovered, and 56 articles, published between 1982 and 2020, were included in this systematic review. These articles were selected based on title, abstract and full text. The technique most used to determine the susceptibility to antimicrobials of E. coli strains was disk diffusion test [83.93% (47/56)], followed by minimum inhibitory concentration test (MIC) [19.64% (11/56)]. Only two studies [3.57% (2/56)] performed both tests. Seventy-eight different antimicrobial drugs of seventeen classes were tested using disk diffusion methodology. For the MIC, fifteen antimicrobial classes and sixty-one antimicrobial drugs were tested. Cephalosporins was the most tested antimicrobial class, both by disk diffusion and MIC methods. Antimicrobials classes with the highest resistance levels were observed for tetracyclines, penicillin’s, folate inhibitors, aminoglycosides, phenicol’s and fluoroquinolones. Due the heterogeneity and low quality of the studies, mainly regarding antimicrobial susceptibility test methodology used, it was not possible to perform metanalysies. Nonetheless, despite that our results showed a high prevalence of AMR among the main classes used in the treatment of gastrointestinal infections caused by E. coli, especially tetracyclines, penicillin, folate inhibitors, macrolides, and aminoglycosides, besides a great pathogenic potential of the strains analyzed considering the virulence profiles and ARG observed. Development Agency: Fapemig, CAPES

Palavras-chave:
 epidemiology, enterobacteriaceae, cattle, antimicrobial susceptibility, enteropathogenic E. coli


Agência de fomento:
Fapemig, CAPES