| Congresso Brasileiro de Microbiologia 2023 | Resumo: 429-2 | ||||
Resumo:The Programa Nacional de Controle e Erradicação de Brucelose e Tuberculose (PNCEBT) was implemented in 2001. Since then, the PNCEBT recommends the use of live attenuated vaccines (S19 and RB51) in female calves, to prevent bovine brucellosis and its reproductive signs. According to the PNCEBT, only accredited veterinarians and vaccinators under responsibility of accredited veterinarians are allowed to perform the vaccination, always using personal protective equipment (PPE) to avoid exposure to the live pathogen. The aim of this study was to investigate the accidental exposure to S19 and RB51 among accredited veterinarians from Federal District, Brazil. All the accredited veterinarians (n =109) in the PNCEBT in the Federal District were interviewed through an online survey, from March to November of 2022. The survey asked about age, gender, professional experience, area of specialization (beef/buffalo beef or milk, dogs and cats, or administrative sector), perceptions of diseases (transmission, signs and symptoms), infection control practices and risk procedures (contact with the live attenuated vaccines and with animals potentially infected with Brucella spp.), in addition to the occurrence of accidental contact with S19 and RB51 vaccines and a self-report of brucellosis. All the variables acquired from the survey were tested for association comparing the groups of exposed and non-exposed by Chi-Square, Fisher exact tests and/or univariate logistic regression. The association results were considered significant with a p-value of <0.05. The results showed a prevalence of 22.94% (25/109) [95% Confidence Interval (CI): 15.43 a 31.97%] of vaccine accident only with S19 vaccine, and the veterinarians that worked with beef cattle had a significant association with the exposure (p-value:0.04), Odds ratio (OR) of 0.27(95% CI 0.05-1.04) when compared with the other areas of specialization (beef/buffalo beef or milk, dogs and cats, or administrative sector). Furthermore, autonomous veterinarians were at less chance of being expose to vaccine accident (OR: 0.264, 95% CI: 0.08- 0.77) (p-valeu:0.04) then those that worked as public servant and/or private companies, and public server veterinarians was the category with more chance of being exposed, with OR of 8.03 (95% CI: 2.73-26.30) (p-value:0.00), compared with autonomous veterinarians and/or veterinarians from private companies. In conclusion, the prevalence of accidental exposure to B. abortus vaccine strains among veterinarians from Distrito Federal enrolled in the control of bovine brucellosis was high and public server veterinarians was the group with the higher chances to be accidentally exposed to S19 and RB51. Palavras-chave: Vaccine, Epidemiology, Brucella abortus Agência de fomento:Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG). | |||||